课程咨询

雅思备考规划

扫码添加助教免费咨询雅思备考规划

扫码关注回复雅思获取最新雅思口语题库和备考资料

雅思阅读临考冲刺模拟试题(19)

2015-04-02 11:41:39来源:网络 柯林斯词典

  下面就是新东方在线雅思网为大家收集整理的雅思阅读临考冲刺模拟试题,供大家参考,希望以下内容能够为同学们的雅思备考提供帮助。更多雅思报名官网的最新消息,最新、最专业的雅思备考资料,新东方在线雅思网将第一时间为大家发布。

  1.The failure of a high-profile cholesterol drug has thrown a spotlight on the complicated machinery that regulates cholesterol levels.But many researchers remain confident that drugs to boost levels of 'good' cholesterol are still one of the most promising means to combat spiralling heart disease.

  2.Drug company Pfizer announced on 2 December that it was cancelling all clinical trials of torcetrapib,a drug designed to raise heart-protective high-density lipoproteins (HDLs).In a trial of 15000 patients,a safety board found that more people died or suffered cardiovascular problems after taking the drug plus a cholesterol-lowering statin than those in a control group who took the statin alone.

  3.The news came as a kick in the teeth to many cardiologists because earlier tests in animals and people suggested it would lower rates of cardiovascular disease."There have been no red flags to my knowledge," says John Chapman,a specialist in lipoproteins and atherosclerosis at the National Institute for Health and Medical Research (INSERM) in Paris who has also studied torcetrapib."This cancellation came as a complete shock."

  4.Torcetrapib is one of the most advanced of a new breed of drugs designed to raise levels of HDLs,which ferry cholesterol out of artery-clogging plaques to the liver for removal from the body.Specifically,torcetrapib blocks a protein called cholesterol ester transfer protein (CETP),which normally transfers the cholesterol from high-density lipoproteins to low density,plaque-promoting ones.Statins,in contrast,mainly work by lowering the 'bad' low-density lipoproteins.

  Under pressure

  5.Researchers are now trying to work out why and how the drug backfired,something that will not become clear until the clinical details are released by Pfizer.One hint lies in evidence from earlier trials that it slightly raises blood pressure in some patients.It was thought that this mild problem would be offset by the heart benefits of the drug.But it is possible that it actually proved fatal in some patients who already suffered high blood pressure.If blood pressure is the explanation,it would actually be good news for drug developers because it suggests that the problems are specific to this compound.Other prototype drugs that are being developed to block CETP work in a slightly different way and might not suffer the same downfall.

  6.But it is also possible that the whole idea of blocking CETP is flawed,says Moti Kashyap,who directs atherosclerosis research at the VA Medical Center in Long Beach,California.When HDLs excrete cholesterol in the liver,they actually rely on LDLs for part of this process.So inhibiting CETP,which prevents the transfer of cholesterol from HDL to LDL,might actually cause an abnormal and irreversible accumulation of cholesterol in the body."You're blocking a physiologic mechanism to eliminate cholesterol and effectively constipating the pathway," says Kashyap.Going up

  7.Most researchers remain confident that elevating high density lipoproteins levels by one means or another is one of the best routes for helping heart disease patients.But HDLs are complex and not entirely understood.One approved drug,called niacin,is known to both raise HDL and reduce cardiovascular risk but also causes an unpleasant sensation of heat and tingling.Researchers are exploring whether they can bypass this side effect and whether niacin can lower disease risk more than statins alone.Scientists are also working on several other means to bump up high-density lipoproteins by,for example,introducing synthetic HDLs."The only thing we know is dead in the water is torcetrapib,not the whole idea of raising HDL," says Michael Miller,director of preventive cardiology at the University of Maryland Medical Center,Baltimore.

  (613 words nature)

  Questions 1-7

  This passage has 7 paragraphs 1-7.

  Choose the correct heading for each paragraph from the list of headings below.

  Write the correct number i-ix in boxes 1-7 on your answer sheet.

  List of Headings

  i.How does torcetrapib work?

  ii.Contradictory result prior to the current trial

  iii.One failure may possibly bring about future success

  iv.The failure doesn't lead to total loss of confidence

  v.It is the right route to follow

  vi.Why it's stopped

  vii.They may combine and theoretically produce ideal result

  viii.What's wrong with the drug

  ix.It might be wrong at the first place

为你特别匹配的雅思超值课程,祝你和雅思分手!
  • 新东方11月雅思公开讲座

    新东方雅思11月公开讲座

    新东方教师直播教你全科技巧!

    每天1小时

    查看详情
  • 雅思机考实战

    雅思机考实战

    剑桥雅思正版题目机考实战!

    每天1小时

    查看详情
  • 【知心雅思】6分录播课 (A类)

    【知心雅思】6分录播课 (A类)

    适合人群:想要冲6分的考生

    课时:434

    查看详情
  • 【知心雅思】6.5分录播课 (A类)

    【知心雅思】6.5分录播课 (A类)

    适合人群:想要冲6.5分的考生

    课时:464

    查看详情
  • 【知心雅思】7分录播课 (A类)

    【知心雅思】7分录播课 (A类)

    适合人群:想要冲7分的考生

    课时:443

    查看详情
雅思备考资料包

扫码添加助教

免费获取雅思备考资料包

更多资料
更多>>
更多内容

移动学习

二维码

2024年9月-12月雅思口语题库

扫码即可免费领取最新雅思口语题库
更多>>
更多公开讲座>>

2024年雅思考试机经

扫码免费领取【雅思考试机经】

考试机经
更多>>
更多资料