frailties
If you refer to the frailties or frailty of people, you are referring to their weaknesses.
the frailties of human nature.
人性的弱点。
Frailty is the condition of having poor health.
She died after a long period of increasing frailty.
在很长一段时间里,她的身体日益虚弱,最后离开了人世。