A loaded question or word has more meaning or purpose than it appears to have, because the person who uses it hopes it will cause people to respond in a particular way.
That's a loaded question.
那是一个意味深长的问题。
If something is loaded with a particular characteristic, it has that characteristic to a very great degree.
The president's visit is loaded with symbolic significance.
总统的访问富有象征意义。
If a place or object is loaded with things, it has very many of them in it or it is full of them.
a tray loaded with cups.
一个盛满杯子的托盘。
The second store you enter is loaded with jewellery.
你进入的第二家商店满是珠宝首饰。
If you say that something is loaded in favour of someone, you mean it works unfairly to their advantage. If you say it is loaded against them, you mean it works unfairly to their disadvantage.
The press is loaded in favour of this present government.
新闻界偏向于现任政府。