There's absolutely no regulation of cigarettes to make sure that they don't include poisonous substances.

没有任何规定来保证香烟不含有毒物质。

The substance that's causing the problem comes from the barley.

造成这个问题的物质来自于大麦。

It's questionable whether anything of substance has been achieved.

是否已取得实质性的进展值得质疑。

The substance of his discussions doesn't really matter.

他讨论的要旨实际上并不重要。

There is no substance in any of these allegations.

这些指控都毫无依据。