Upstream is used to refer to something that is towards the source of a river.
We'll go to the upstream side of that big rock.
我们要去那块大岩石的上游一侧。
Something that is moving upstream is moving towards the source of a river against the current, from a point further down the river. Something that is upstream is towards the source of a river.
Salmon manage to swim upstream to lay their eggs.
三文鱼设法游到上游产卵。
the river police, whose headquarters are just upstream of the Ile St Louis.
总部就设在圣路易斯岛上游的水警。